Scientific Papers - April 2022

In the month of April, the WFADHD is delighted to highlight the following two papers:

There is evidence that ADHD is associated with poor somatic health in adulthood. However, the mechanisms underlying these associations are elusive. Garcia-Agibay et al. tested whether ADHD polygenic risk scores are associated with mid-to-relate life somatic health in a general population sample. Results showed that higher ADHD polygenic risk scores (PRS) were associated with increased risk of seven somatic outcomes and findings suggests that higher ADHD genetic liability convers a modest risk increase for several somatic health problems in mid-to-late life, particularly in the cardiometabolic domain.

Population trajectories of ADHD spanning early childhood to mid-life are crucial to better understand typical developmental patterns. Wootton et al. combined repeated assessments of ADHD traits from five population-based cohorts to analyse patterns of age-related change in ADHD trait scores. The findings suggests that ADHD trait scores declined from childhood to mid-life, with marked variation between cohorts.